Calbiotech HSV 2 IgG Elisa Kit

Product Description

HSV-1 and 2 are virtually identical, sharing approximately 50% of their DNA and have over 80%of common antigens. Both types infect the body's mucosal surfaces, usually the mouth orgenitals, and then establish latency in the nervous system. For both types, at least two-thirds ofinfected people have no symptoms, or symptoms too mild to notice. However, both types canrecur and spread even when no symptoms are present. By the time they're teenagers or youngadults, about 50% of Americans have HSV-1 antibodies in their blood. By the time they are overage 50, some 80-90% of Americans has HSV-1 antibodies. By comparison, almost all HSV-2 isencountered after childhood, when people become sexually active. HSV type 1 is the cause ofmost orofacial herpes and HSV encephalitis; type 2 is the primary cause of initial and recurrentgenital herpes and neonatal HSV. Reactivation of latent HSV infection is a frequent complicationof immunosuppression due to cancer, transplantation and AIDS. Asymptomatic genital sheddingof HSV-2 is more common than HSV-1 and occurs more frequently during the first 3 monthsafter acquisition of primary type 2 disease than during later periods.